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A biomarker is defined as a characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions

Ensure patent venous access prior to administration of ProvayBlue

Because TB-500 builds up a systemic presence, a 4-week cycle ensures that the subject does not reach an over-saturated level where the actin-sequestering effect becomes counterproductive

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Each patient was instructed to reconstitute the powder using 1.1 mL of sterile water and self-administer the drug via subcutaneous injection of the period of the study