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The dangers come from how the treatment is delivered in the unregulated market
doi: 10.1016/j.freeradbiomed.2014.09.015 132 XiaoMZhongHXiaLTaoYYinH
The combination of prednisone and acetaminophen is safer because there are no dangerous interactions between that pain reliever and steroids
Inorganic Chemistry, 51 (11), 62856298