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By inhibiting NF-B activation, NAC effectively diminishes the transcription of these inflammatory mediators, thus mitigating the neuroinflammatory cascade [52]

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We also noted that GSTO1 expression was higher in several colorectal cancer patient tumours as compared with normal colon tissue, consistent with our bioinformatics analysis (Supplementary Fig

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Activated protein C however has not been explored for its protection over BBB integrity in the context of MS, but rather for its anti coagulation effects, reducing disease severity in MS models [128]