Patients must evaluate whether the potential for improved health and weight loss justifies the risk of experiencing these side effects
Underweight 30 Your estimated weight loss outcome A maximum loss of 20% Clinical studies have found that semaglutide (GLP-1) led to an average weight loss of about 15% over 68 weeks, with some individuals losing as much as 20%, when used alongside a lower-calorie diet and increased physical activity
Note: The Medicaid version of the BALANCE Model is still launching in May 2026, but that is entirely separate from Medicare Part D
Continue to convey the message: You are not alone. Help your patients prevent semaglutide rebound weight gain As GLP-1 medications like semaglutide become increasingly common, GPs are key to helping patients navigate life after treatment
Understanding that constipation results from slowed gut motility, reduced food intake, and decreased fiber consumption helps you address it effectively through aggressive hydration, prioritizing fiber intake, maintaining physical activity, and using safe, effective treatments like polyethylene glycol when needed