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The idea is that targeting multiple pathways involved in appetite and fullness could lead to greater weight loss than using either approach alone

Cell treatments and cell death assays EndoC-H1 cells, dispersed human islets, iPSC-derived beta cells, NPCs and cerebellar neurons were exposed to the ER stressor tunicamycin (5 g/ml), thapsigargin (1 mol/l) or brefeldin A (0.05 g/ml), alone or combined with exenatide (50 nmol/l in beta cells, 500 nmol/l in neurons), dulaglutide (50 nmol/l) or forskolin (20 mol/l)

This repositioning fundamentally changes how providers evaluate eligibility and outcomes

Healthcare Professionals to learn more about disease states investigated by Novo Nordisk and our related products.