semaglutide and uti symptoms Does Rybelsus Cause UTI? Evidence Guidance – Bolt Pharmacy Patient Basics: Urinary Tract Infection

GLP-1 agonists like semaglutide (Ozempic) act primarily on metabolic and interoceptive systemstargeting hypothalamus, brainstem, and nucleus tractus solitariusbut they also modulate reward circuitry, including the nucleus accumbens and ventral tegmental area

For context: the SELECT trial showed that subcutaneous semaglutide 2.4 mg reduced the risk of major adverse cardiovascular events by 20% in adults with established cardiovascular disease and overweight or obesity but without diabetes (Lincoff AM et al., 2023, New England Journal of Medicine , doi:10.1056/NEJMoa2307563 PMID 37952131)

S., Schirlo, J

As estrogen declines, that pattern shifts

Adequate hydration - Staying hydrated helps maintain metabolic function, supports digestion, and can reduce feelings of false hunger that may lead to overeating