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#RegulatoryAffairs #ClinicalTrials #FDAApproval #Virology #PublicHealth #PharmaNews To view or add a comment, sign in In two phase 3 clinical trials, roughly one in five adults with chronic hepatitis B achieved sustained loss of hepatitis B surface antigen (HBsAg) and undetectable hepatitis B viral DNA after completing a finite course of bepirovirsen treatment

Timing patterns from pooled data The STEP trials pooled data reveals several important timing patterns: The incidence of new-onset nausea was highest during the dose escalation period (weeks 1 to 20) and decreased substantially once participants reached maintenance dosing

Weight change usually appears after the first month and often plateaus by six months

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Some pharmacies also offer 15mg or 20mg vials for people who need long-term supplies or who are splitting vials among family members for cost savings