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Mechanism & Research Background Melanotan II is a synthetic cyclic lactam analog of the -MSH core sequence, constrained by a lactam bridge between its Asp and Lys residues to resist enzymatic degradation and increase receptor affinity

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10.1016/B978-0-7020-5307-8.00020-X Supplements to Clinical neurophysiology 111 ZhangH.ZhangL.ZhouD.HeX.WangD.PanH.et al (2017)

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In contrast, for simvastatin, the IC50 value in HEB was significantly higher than that in glioblastoma cell lines (Fig

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