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The compound's selectivity for NNMT over other methyltransferases is critical
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Preclinical studies use the pairing to probe parallel effects on growth-factor signalling, cytoskeletal remodelling, and angiogenic responses in vitro
On-Target, Off-Tumor Effects in Targeted Therapies: In contrast to cytotoxic agents, targeted therapies are designed to selectively inhibit molecular pathways involved in tumor growth
Fyn amplifies NLRP3 inflammasome signaling in Parkinson's disease
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