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However, alterations in gut homeostasis characterized by changes in the composition of the gut microbiota, microbial products, antimicrobial peptide levels and mucosal barrier disruption play a major role in the onset and progression of liver diseases including two prevalent diseases, alcohol-associated liver disease (ALD) and metabolic dysfunction-associated steatotic liver disease (MASLD) (911, 13, 18, 19)

Reasonable approaches include: Stabilization approach: Wait until Ozempic dose is titrated to maintenance level and side effects have stabilized, typically 4-8 weeks

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Characterization of skeletal muscle endocrine control in an in vitro model of myogenesis