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Patel et al., Vitamins, Amino Acids, and Drugs and Formulations Used in Nutrition, 2016, pp

Mild digestive discomfort is one of the most commonly reported reactions

On April 23, 2026, at DAAs request Council authorized an amendment to the management agreement to extend the term to April 30, 2031, and update the 5-year Service and Assessment Plan and Budget to align with the extended term ( Council Item #11 & Council Item #12 )

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Limited long-term human safety data for most compounds, with evidence generally drawn from short trials, animal studies, or research on a different indication