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Lauring J, Park BH, Wolff AC

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The condition is characterized by a breakdown in the blood-brain barrier, and symptoms drastically improve when thiamin levels are restored

At subtoxic concentrations, H 2 S has been shown to stimulate ATP production at the level of oxidative phosphorylation, both as a source of electron equivalents for the mETC (via SQR-mediated quinone reduction, Table 1), and through per-sulphidation of ATPase, which maintains the enzyme in its activated state