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doi: 10.1016/j.ijcha.2020.100529 137 McMahonMSkaggsBGrossmanJWongWKSahakianLChenWet al

Eric Hollander, MD Dr

3.2 DNA fragmentation In addition to lipid peroxidation, oxidative stress induces significant damage to sperm DNA, leading to DNA fragmentation ( Figure 2 )

Prez-Martn J, Bardetti P, Castanheira S, de la Torre A, Tenorio-Gmez M

Although often presented as a broadly beneficial polyphenol, resveratrol has also been repeatedly flagged as a potentially PAINS-susceptible molecule, owing to its redox activity, metal-chelating properties, and tendency to interfere with multiple assay formats in a non-specific manner as highlighted in the Nature commentary ( Weight of evidence: Overall evidence is Low : an add-on signal on hyperactivity without core-symptom change