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61 A working core outcome set for CLE trials was recently developed to guide future clinical and outcomes research in CLE, recommending the CLASI as a primary endpoint and the Cutaneous Lupus Activity IGA (CLA-IGA) as a secondary endpoint for CLE physician-reported outcome measures

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The acid in the present invention can be selected from but not limited to inorganic acids selected from hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid, boric acid, perchloric acid