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A study showed that induction of ferroptosis by blocking Nrf2-Keap1 pathway also sensitizes cisplatin-resistant GC cells to cisplatin (Ouyang et al., 2022)

Furthermore, degenerative changes of multiple organs, including the liver and glomerular and tubular epithelium, were observed

Sintoni, S., Kurtys, E., Scandaglia, M., Contestabile, A

Glutathione helps by inhibiting tyrosinase and balancing oxidative stress, which indirectly reduces melanin overproduction responsible for pigmentation and melasma

The original publication : Reduced Intestinal GLP-1+ Cell Numbers Are Associated With an Inflammation-related Epithelial Metabolic Signature