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In experimental research it is used as a tool compound to investigate extracellular matrix modulation, collagen and elastin synthesis, angiogenesis, and gene expression changes in in vitro and in vivo tissue-repair models

This phenomenon, known as an osmotic shift, occurs when fluid shifts between blood vessels and cells due to a sudden change in sugar concentration

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doi: 10.1523/JNEUROSCI.2893-16.2017 33 FiliceFJanickovaLHenziTBilellaASchwallerB

Indole-3-acetic acid, malonyl-coenzyme A, N-acetyl cysteine, serotonin and vitamin B12 were purchased from Sigma-Aldrich