If low levels of B 12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms: numbness and tingling in the hands and feet difficulty walking muscle weakness irritability memory loss dementia depression psychosis
[PUBMED Abstract] Syndromes Associated With Rare Types of Skin Cancer Brooke-Spiegler Syndrome, Multiple Familial Trichoepithelioma, and Familial Cylindromatosis Brooke-Spiegler Syndrome (BSS), familial cylindromatosis, and multiple familial trichoepithelioma (MFT) are all autosomal dominant syndromes with overlapping clinical characteristics with allelic variance.[1] Features of BSS include multiple skin appendage tumors such as cylindromas (tumors arising in the hair follicle stem cells), trichoepitheliomas (tumors arising in the hair follicle), and spiradenomas (benign tumors arising in the sweat gland)
They can also have preserved muscle mass with profound weakness myosteatosis, anabolic resistance
It exists, but it doesn't hold up as well under the daily demands your skin faces
10.1016/j.lf10.1016/j.lfs.2011.01.015 37 IlicS.DrmicD.ZarkovicK.KolencD.CoricM.BrcicL.et al (2010)