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Moreover, UV radiation can activate the proopiomelanocortin (POMC) gene and thereby enhance the production of alpha-melanocyte stimulating hormone (-MSH) and adrenocorticotropic hormone (ACTH) which can lead to increased PKA and melanogenesis (Im et al., 2002)

Cell Mol Neurobiol 41(1):173183 Taskiran AS, Ergul M (2021) The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line [J]

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For peptide reconstitution and research applications, HPLC purity above 98% is generally considered acceptable