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Valproate should not be used to treat women with epilepsy or bipolar disorder who are pregnant or who plan to become pregnant unless other medications have failed to provide adequate symptom control or are otherwise unacceptable

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

For the full list, see the DSRIP Project Toolkit

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This is one reason L-carnitine has been studied in clinical nutrition settings, although supplementation for medical conditions should always be guided by healthcare professionals