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For a complete overview of MOTS-c's mechanism and biology, see the MOTS-c peptide profile

doi: 10.1016/j.pnpbp.2024.111018 173 PatlolaSRDonohoeGMcKernanDP

In general, ROS signaling in eryptosis is less diverse compared to nucleated cells, since in erythrocytes, ROS mainly mediate PS externalization by modulating Ca 2+ influx, while in nucleated cells, there are multiple signaling pathways downstream of ROS involved in the execution of apoptosis

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