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Only in very rare cases where an inadvertent rechallenge occurs do symptoms appear within hours

For instance, Brandts and his team confirmed that polystyrene nanomaterials interfere with lipid metabolism through the PPAR system and affect the functionalization of macrophages [69]

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By the end of the 1990s, the introduction of SLNs marked a critical advance- researchers had moved beyond simple emulsions to true nanostructured carriers that offered both protection and better retention of sensitive nutraceutical ingredients