The studied GLP-1 RAs included exenatide [14, 35, 37, 39], liraglutide [27, 36,37,38,39], semaglutide [27, 34, 37,38,39], lixisenatide [37, 39], dulaglutide [37, 39], albiglutide [39] and the dual agonist (GLP-1 and Glucose-dependent insulinotropic polypeptide (GIP)) tirzepatide [29, 37]
Researchers continue investigating which receptor combinations produce optimal outcomes for different patient populations
Some drugs combine multiple hormones, while others, like eloralintide, explore entirely different pathways
A 43-year-old woman with a 25-year history of Crohn's disease including bowel resection and severe bile acid malabsorption shared her experience after 15 days on a split-dose retatrutide protocol
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