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Neuropsychopharmacology 33, 5672

Quite unexpectedly, EDRF was found to be the free radical diatomic gas, nitric oxide , NO

Novel therapeutic approach: organic arsenical (melarsoprol) alone or with all-trans-retinoic acid markedly inhibit growth of human breast and prostate cancer cells in vitro and in vivo

However, the considerable increase in its content in the air since the end of the 19th century (its concentration has risen from 290 ppm at the beginning of the Industrial Revolution to nearly 420 ppm today), raises questions about the ability of plants to regulate this increased carbon input

[5] Sustained NO Production - L-citrulline creates a longer-lasting elevation of plasma arginine levels compared to direct L-arginine supplementation, providing extended NO production benefits