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As shown in Supplemental Figure 5, B and C, we observed lower Na/K/Cl cotransport and Na/H exchange activities in RBCs from mitapivat-treated 4.2 / mice when compared with vehicle-treated animals, suggesting an improved RBC ion homeostasis related to the amelioration of RBC membrane mechanical stability

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Cancer-associated fibroblast-induced lncRNA UPK1A-AS1 confers platinum resistance in pancreatic cancer via efficient double-strand break repair

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