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A case in point, when 2 different mouse strains were exposed to therapeutic or hepatotoxic doses of APAP, depletion of GSH or APAP protein adduct formation was only detected in the liver but not in the whole brain or individual brain regions, suggesting that there is no evidence for the formation of the reactive metabolite NAPQI in the brain of adult mice [185]

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Although free radical reactions are necessary for the defense mechanism of cells such as neutrophils and macrophages from immune system cells, overproduction of free radicals results in tissue damage and cell death [3]

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(6) L-glutatyon takviyeleri L-glutatyon takviyeleri, zellikle yalandka glutatyon retimi azaldnda veya baz salk durumlaryla ilikili olarak dk glutatyon seviyeleri olduunda tercih edilebilir

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