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Researchers monitored changes in body mass index (BMI), weight, flare frequency, Dermatology Life Quality Index (DLQI) value, and pain levels before and after starting semaglutide, as well as biochemical markers, including C-reactive protein (CRP), glucose and hemoglobin A1c (HbA1c) levels

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The core reactions of the ISR involve eIF2 phosphorylation and elevated ATF4 expression, both of which are closely linked to oxidative stress and various neurodegenerative diseases [170,171,172,173,174]