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Mice were euthanized ~24 h after the last gavage

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Studies in Crat knockout mice demonstrated that CrAT deficiency leads to abnormal fuel selection, which results in a perturbation of glucose homeostasis and suggest that deficits in CrAT activity might contribute to diet-induced metabolic inflexibility by exacerbating the Randle glucose-fatty acid cycle 66

During the menopause transition, women frequently experience shifting hormones, sleep issues, and body composition changes like more belly fat and less muscle

Importantly, they also measured physical performance too (7)