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This could lead to an increase in calorie burning and a reduction in fat storage

PMID: 41931110 Bioconjug Chem Development of a Long-Acting and Stapled Dual Amylin and Calcitonin Receptor Agonist as Monotherapy and Combination with GLP-1R Agonists for the Treatment of Obesity

If nausea becomes severe despite pyridoxine, ondansetron (Zofran) is a prescription anti-nausea medication that many providers prescribe as a rescue option

It is important to note that having potential risk factors does not preclude tirzepatide use, but rather indicates the need for patient education, appropriate monitoring during treatment initiation, and readily available emergency management resources

Clinical trials have demonstrated that the use of 2.4 mg of semaglutide once a week, combined with lifestyle intervention, led to a persistent and clinically significant reduction in body weight, with an average reduction of 14.9%