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In a 2022 study, Santoro found that after 16 weeks of exercise, meal control, and the over-the-counter drug orlistat (Alli), we did not see an improvement in pregnancy rate. In a similar 2016 study in the Netherlands, the weight-loss intervention resulted in a slight decrease in the pregnancy rate

It is not clear whether HRT mitigates or promotes the processes that drive MASLD, and this is particularly concerning as HRT is becoming a more prevalent treatment option

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However, the interest in GLP-1 goes beyond celebrity endorsements

So dont be afraid to take moderate to high doses of vitamin B12