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Single-cell RNA sequencing reveals expanded clones of islet antigen-reactive CD4 + T cells in peripheral blood of subjects with type 1 diabetes

The elucidation of mechanisms by which TMAO aggravates kidney disease injury seems to have made preliminary progress, laying the foundation for a more comprehensive description of the molecular mechanisms by which TMAO causes kidney disease

In a large safety and efficacy data analysis of 1,783 patients receiving Avelumab from the Merkel 200 trials and the JAVELIN Solid Tumor, 16% (295 patients) developed irAEs

doi: 10.1093/jxb/erv063 32 HllerK.KirlyL.KnstlerA.MllerM.GullnerG.FattingerM.et al