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This form is not easily absorbed, produces a cyanide molecule that must be detoxified by the liver and it requires extra energy from our body for proper metabolism (22)
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SREBP1c expression is enhanced in patients with NAFLD, and in agreement with its lipogenic role, hepatic triglyceride levels are higher in transgenic mice overexpressing SREBP1c [44, 45], while SREBP1c knockout mice display decreased expression of lipogenic enzymes [46]