Discussion This umbrella review systematically reviewed 123 meta-analyses encompassing 464 outcomes on GLP-1 RAs across various populations
In particular, osteoporotic fractures result in significant pain, functional impairment, and loss of independence, imposing substantial socioeconomic and psychological burdens on patients and caregivers ( Current therapeutic strategies for OP primarily include antiresorptive agents (e.g., bisphosphonates), anabolic drugs (e.g., parathyroid hormone analogs), hormone replacement therapy, and supplementation with calcium and vitamin D
rosea extract (340 mg standardized to a content of rosavin 3.07%/rhodioloside 1.95%), sertraline (50 mg HCI), or a placebo
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