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It is important to note that A negative Intrinsic Factor antibody result does not exclude the diagnosis of PA as only 60% of patients with PA will have this antibody

This is an observed phenomenon where the peptides ability to accelerate cell turnover brings underlying congestion (such as microcomedones or trapped sebum) to the surface more quickly

In some cases, individuals may also experience regurgitation of food or sour liquid, which can further exacerbate the discomfort and lead to a restless nights sleep