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A qualified clinician should review the patients diagnosis, conventional options, medications, allergies, pregnancy status when relevant, organ function, prior reactions, goals, and ability to participate in monitoring

Avoid excessive amounts, which can increase irritation risk

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NICE-approved weight management interventions include: Dietary and lifestyle modification first-line approach for all patients Orlistat licensed medication for obesity (BMI 30 or 28 with comorbidities) GLP-1 receptor agonists including semaglutide (Wegovy) per NICE TA875 and liraglutide (Saxenda) with restrictions per NICE TA664, for specific patient groups Bariatric surgery for severe obesity meeting strict criteria The NHS emphasises that sustainable weight loss requires behavioural change, nutritional education, and increased physical activity

Heavy drinking, in particular, can lead to cardiomyopathy, a chronic disease of the heart muscle