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doi: 10.3389/fendo.2021.814770 Received 14 November 2021 Accepted 13 December 2021 Published 10 January 2022 Volume 12 - 2021 Edited by Cristina Giaroni, University of Insubria, Italy Reviewed by Eliana Piantanida, University of Insubria, Italy

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TB-500 / thymosin beta-4 is usually discussed more broadly around cell migration, actin dynamics, angiogenesis, and general tissue-repair signalling

The predominance of CKD accounts for the increased mortality observed in people living with T2DM [5]

Although not a direct causality of probiotic supplement, the results obtained here, when taken together, provide new insights to investigate further the effect of this probiotic combination such as the impact of the family Porphyromonadaceae and inhibition of the growth of opportunistic pathogens