Figure 3 3.1 TLR-nuclear factor kappa B signaling pathway As one of the earliest identified PRR families, TLRs comprise 10 members in humans (TLR1-10) and 12 in mice (TLR1-9, 11-13) ( Simultaneously, the IRAK-TRAF6 complex activates mitogen-activated protein kinase kinase (MKK) cascades, thus leading to activation of activator protein 1 (AP-1), which is another critical transcription factor in inflammation ( Figure 4 )

Aqua / Water / Eau, Aloe Barbadensis Leaf Juice, Vaccinium Myrtillus Fruit Extract, Sodium Hydroxide, Hamamelis Virginiana Water / Witch Hazel Water, Saccharum Officinarum Extract / Sugarcane Extract / Extrait De Canne A Sucre, Chamomilla Recutita Flower Extract / Matricaria Flower Extract, Acer Saccharum Extract / Sugar Maple Extract, Citrus Aurantium Dulcis Fruit Extract / Orange Fruit Extract, Citrus Aurantium Dulcis Oil / Orange Peel Oil, Citrus Limon Fruit Extract / Lemon Fruit Extract, Pvp, Isoceteth-20, Disodium Edta, Propylene Glycol, Citric Acid, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Chlorphenesin, Limonene (F.I.L
It makes bones fragile and more likely to break
10.1111/j.1399-3089.2007.00419.x 137 ViswanathanP.GuptaP.KapoorS.GuptaS
Patients can present with symptoms related to anemia, such as fatigue or dyspnea