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Compounds 78 , 79 , and 80 showed IC 50 values of less than 0.6 M for XO inhibitory activity and for AChE, the IC 50 values showed the same trend, with values of less than 1.0 M (Table 4)

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Antiepileptic Drugs (e.g., Phenytoin, Phenobarbital) Effect: May alter Vitamin B levels and reduce therapeutic effectiveness

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Additional studies have explored dopaminergic and serotonergic modulation in traumatic brain injury models [2], though these neuroprotective findings remain early-stage and preclinical