The final yield of recombinant mGH obtained from the F1 peak from anion exchange chromatography was 3.7 mg from 1 L of culture medium
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Lebers hereditary optic neuropathy first causes central vision loss which can progress to blindness by early or middle adulthood (Puomila 2007)
Oral administration of 10 mg/kg of EGCG from a presymptomatic stage delays the onset of the disease and prolongs useful life, in addition to increasing the number of motor neurons, decreasing the activation of the microglia, reducing the concentration of NF-kB, caspase-3 and iNOS in a transgenic mouse model of ALS (Xu et al., 2006) (Table 1)
- has anti inflammatory effect