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Passive diffusion also occurs throughout the intestinal tract, allowing approximately 1% of oral doses to be absorbed without intrinsic factor

28 days is the FDA requirement for producers of multi-use vials to prove their bacteriostatic maintains efficacy

Evidence: What does the current research actually support, and how preliminary is it

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401 A meta-analysis of five randomized controlled trials with a total of more than 11,000 participants found colchicine reduced the risk of major thromboembolic cardiovascular events in patients with coronary artery disease, but had no effect on cardiovascular mortality