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These linkers include the GFLG peptide which is cleaved by cathepsin B 75 , the PLGLAG peptide which is cleaved by matrix metalloprotease (MMP)-2/9 76 , and the oxime-hydrazone bond which is hydrolyzed in an acidic pH 77

But the higher doses required for weight loss (absent a diabetes diagnosis) create more side effects, and at the end of the day, they arent cost-effective

15 Potential Additional Benefits Several studies have investigated potential additional benefits of DPP-4 inhibitors, including microvascular and macrovascular effects, effects on blood pressure (BP) and weight, and risk of hypoglycemia

Derecho a la portabilidad de los datos: Tiene derecho a obtener sus datos en formato electrnico y a solicitar que los transmitamos directamente a otra organizacin cuando sea tcnicamente posible

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