Much larger injection volumes, even up to 10 mL or more, can now be delivered subcutaneously, with 25 mL being studied in a recently published study in the absence of a permeation enhancer.2 In some cases, co- or subsequent administration of hyaluronidases (enzymes that locally and transiently digest the SC tissue) can facilitate administration of larger injection volumes by reducing SC tissue back pressure.3 Using innovative SC delivery devices, such as on-body injectors (OBIs), including West Pharmaceutical Services SmartDose or Ypsomeds YpsoDose, can also facilitate larger-volume SC injections without a permeation enhancing enzyme
For example, a carbapenem-resistant K
The SCA is the entry point for county-funded substance use assessment and referral
Supercritical CO 2 Extraction of Fingerroot Dried powder of fingerroot rhizome with moisture less than 3.5% w/w was extracted by supercritical carbon dioxide extraction
Kochi, Kerala, India: Society of Fisheries Technologists