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avoiding high-fat foods Temporary dose reduction Stepping back to previous dose if symptoms severe Antiemetic support When appropriate under medical supervision Contraindications and Precautions Certain populations should exercise particular caution with cagrilintide: Personal or family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Severe gastrointestinal disease History of pancreatitis Pregnancy or breastfeeding These contraindications overlap significantly with those for GLP-1 receptor agonists like tirzepatide, making combination approaches even more critical to approach cautiously

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It has undergone numerous human clinical trials (Phase I/II) but has not pursued further regulatory development

Pharmacogenomics, other phenotypes we don't really know why some people only lose 5% where some people are super responders and losing 30% of their body weight