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Advantage : Neither (tie) Weight Loss Efficacy# MET-097i : Phase 2b VESPER-1 showed up to 14.1% mean placebo-subtracted weight loss after 28 weekly doses

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By targeting these pathways, Semaglutide helps: Suppress appetite, making it easier to control portions

5.3 Diabetic Retinopathy Complications In a pooled analysis of glycemic control trials, patients reported diabetic retinopathy related adverse reactions during the trial (4.2% with semaglutide tablets and 3.8% with comparator) [see Adverse Reactions (6.1)]

The mean age across all study cohorts was 58.8 years, ranging from 54 to 64.6 years