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They often complained of low energy and motivational deficits

Various chemical inducers of the NRF2 activity have been identified in the last two decades, but several of these compounds still have significant drawbacks associated to their clinical potential: suboptimal pharmacokinetics (concentration vs

The compounds ability to activate the Nrf2-mediated antioxidant response helps mitigate the collateral damage caused by radiation and chemotherapy, particularly in highly vulnerable tissues such as hematopoietic systems and mucosal barriers ( 5.2 Clinical evidence and trial outcomes The translation of SFN from preclinical models to human clinical applications has generated substantial evidence supporting its potential in cancer prevention and management

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These results are similar to those reported in the three trials described in Table 1 of this paper, which showed improvement in cognitive performance tests, behavior, and well-being of patients given NAC supplementation