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8 Ex vivo studies further confirmed GAPs efficacy in reducing oxidative deoxyribonucleic acid (DNA) lesions and cyclobutene pyrimidine dimers under UVA and UVB irradiation, respectively, though these findings were limited by the small number of biomarkers evaluated
Before now, it has not been possible to deliver such high doses of supplemental glutathione in a way that guarantees maximum absorption for systemic effects
doi:10.1093/clinchem/42.3.416
Synthetic compounds such as dimethyl fumarate (DMF) and its major metabolite monomethyl fumarate are synthetic compounds that have been proven to activate the NRF2 pathway [458]
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