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The pharmacokinetic parameters in this study were as follows: maximum plasma concentration (C max ), time to reach the maximum plasma concentration (T max ), area under the plasma concentrationtime curve from 0 to 72 h (AUC 0-72 ), area under the plasma concentrationtime curve from time 0infinity, absolute bioavailability, accumulation ratio, mean residence time (MRT), volume of distribution (Vd), total clearance (CL), and elimination half-life

BAPN also re-sensitizes triple-negative breast cancer cells to chemotherapy as seen in different triple-negative breast cancer models, including chemoresistant xenografts, syngeneic tumors and PDX models [99]

The peptide dosing guide discusses timing considerations that may affect peptide effectiveness for various applications

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doi:10.1002/vms3.779