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Collagen production declines about 1% per year from the mid-20s onward

[21] [22] Studies of progeroid (premature aging) syndromes, which mimic the clinical and molecular characteristics of aging, have provided some insight into the mechanism of action of NAD+ replenishment

Both raise IGF-1, both carry the GH axiss theoretical risks, and only tesamorelins risk profile has actually been characterized in trials

It recovers on its own timeline, and the data on receptor density recovery makes that timeline clear

A 1012 week on-cycle at the descending frequencies works out to roughly: activation 28 daily doses, consolidation 20 doses (5/wk 4 wks), and 24 maintenance weeks 612 doses call it ~5460 doses for the whole cycle, or about two 30-dose vials