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hCiPSC treatment contributed to a partial recovery, suppressing Clostridiaceae and uniquely enriching Bifidobacteriaceae

Interestingly, AMD3100 reversed this benefit, producing a 55% increase in nitrotyrosine compared to DOX + GHRP-6, further implicating CXCR4 in regulating oxidative stress

In CRC, combining 5FU with DNA-damaging agents oxaliplatin and/or irinotecan was an empirical choice rather than a rationally designed strategy, and no new combination partners have been added since the introduction of the biological EGFR and VEGF-targeting agents in the early 2000s

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Anlotinib combined with osimertinib reverses acquired osimertinib resistance in NSCLC by targeting the c-MET/MYC/AXL axis