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We assume that the effect of DTT is indirect, for example it might function by reducing GSSG, which accumulated in the cell during GSH starvation, to GSH

In the current study, depriving RPE cells of the essential GSH precursor Cys 2 by culturing cells in Cys 2 -free culture medium or blocking de novo synthesis of GSH by using GCL inhibitor BSO or blocking Cys 2 uptake by pharmaceutical inhibition of system x c caused cell death

Structural and energetic basis for novel epicatechin derivatives acting as Gper agonists through the Mmgbsa method

Therefore, there does not appear to be a simple relationship where obesity-induced reduction in ghrelin levels leads to the reduced secretion of GH