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279 The phase 3 HELIOS-B trial (NCT04153149), a multicenter, double-blind, randomized controlled trial, recently reported that vutrisiran reduced the primary endpoint, a composite of all-cause mortality and recurrent cardiovascular events, by 28% in the overall population and by 33% in the monotherapy subgroup

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Tirzepatide helps with weight loss by: Reducing appetite and cravings Improving fullness after meals Stabilizing blood sugar Supporting healthier insulin responses What about its effects on fat cells